Accelerated cardiac MR stress perfusion with radial sampling after physical exercise with an MR-compatible supine bicycle ergometer.
نویسندگان
چکیده
PURPOSE To evaluate the feasibility of accelerated cardiac MR (CMR) perfusion with radial sampling using nonlinear image reconstruction after exercise on an MR-compatible supine bike ergometer. METHODS Eight healthy subjects were scanned on two separate days using radial and Cartesian CMR perfusion sequences in rest and exercise stress perfusion. Four different methods (standard gridding, conjugate gradient SENSE [CG-SENSE], nonlinear inversion with joint estimation of coil-sensitivity profiles [NLINV] and compressed sensing with a total variation constraint [TV]) were compared for the reconstruction of radial data. Cartesian data were reconstructed using SENSE. All images were assessed by two blinded readers in terms of image quality and diagnostic value. RESULTS CG-SENSE and NLINV were scored more favorably than TV (in both rest and stress perfusion cases, P < 0.05) and gridding (for rest perfusion cases, P < 0.05). TV images showed patchy artifacts, which negatively influenced image quality especially in the stress perfusion images acquired with a low number of radial spokes. Although CG-SENSE and NLINV received better scores than Cartesian sampling in both rest and exercise stress perfusion cases, these differences were not statistically significant (P > 0.05). CONCLUSION We have demonstrated the feasibility of accelerated CMR perfusion using radial sampling after physical exercise using a supine bicycle ergometer in healthy subjects. For reconstruction of undersampled radial perfusion, CG-SENSE and NLINV resulted in better image quality than standard gridding or TV reconstruction. Further technical improvements and clinical assessment are needed before using this approach in patients with suspected coronary artery disease.
منابع مشابه
Low latency iterative reconstruction of first pass stress cardiac perfusion with physiological stress using graphical processing unit
Background Cardiac MR perfusion has been shown to provide high diagnostic accuracy in detection of the coronary artery disease [1]. We have recently installed an MR-compatible supine bicycle mounted on the scanner table, which allows performing CMR perfusion immediately after physiologic stress. However, patients are unable to sustain a breathold after physical exercise, limiting the choice of ...
متن کاملExercise stress CMR in patients with coronary heart disease - preliminary results
Background Cardiac stress MRI has grown to a well established method to detect hypokinesia or perfusion deficits due to ischemia. Commonly, myocardial load is generated by the administration of adenosine or dobutamine, which is associated by a higher complication rate compared to exercise stress testing. Our purpose was to evaluate the use of an MR conditional pedal ergometer for cardiac stress...
متن کاملDiagnostic Performance of Treadmill Exercise Cardiac Magnetic Resonance: The Prospective, Multicenter Exercise CMR's Accuracy for Cardiovascular Stress Testing (EXACT) Trial
BACKGROUND Stress cardiac magnetic resonance (CMR) has typically involved pharmacologic agents. Treadmill CMR has shown utility in single-center studies but has not undergone multicenter evaluation. METHODS AND RESULTS Patients referred for treadmill stress nuclear imaging (SPECT) were prospectively enrolled across 4 centers. After rest (99m)Tc SPECT, patients underwent resting cine CMR. In-r...
متن کاملLow Cost Magnetic Resonance Imaging-Compatible Stepper Exercise Device for Use in Cardiac Stress Tests.
Cardiovascular disease is the leading cause of death worldwide. Many cardiovascular diseases are better diagnosed during a cardiac stress test. Current approaches include either exercise or pharmacological stress echocardiography and pharmacological stress magnetic resonance imaging (MRI). MRI is the most accurate noninvasive method of assessing cardiac function. Currently there are very few ex...
متن کاملFlow during exercise in the total cavopulmonary connection measured by magnetic resonance velocity mapping.
OBJECTIVE To measure caval and pulmonary flows at rest and immediately after exercise in patients with total cavopulmonary connection (TCPC). DESIGN An observational study using the patients as their own controls. SETTING Using a combination of magnetic resonance (MR) phase contrast techniques and an MR compatible bicycle ergometer, blood flow was measured in the superior vena cava, the tun...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Magnetic resonance in medicine
دوره 74 2 شماره
صفحات -
تاریخ انتشار 2015